Ashton United will host local rivals Stalybridge Celtic in the pick of the Integro League Cup first-round ties involving our teams.
The Robins will welcome Celtic to Hurst Cross on Tuesday 17 September, hoping to exact revenge for the sides' league meeting on Bank Holiday Monday when goals from Scott Bakkor and Craig Hobson earned a 2-0 win for Stalybridge.
Meanwhile, on the same evening, Glossop North End will travel to Broadhurst Park to face FC United of Manchester.
Monday's draw also confirmed that Droylsden will travel to Radcliffe Borough and Mossley will make the trip to Merseyside to take on City of Liverpool.
Hyde United, along with holders Trafford FC, have received a bye to the second round.
There will be no replays in the first round, so if ties are level after 90 minutes, there will be penalties to determine which team will progress.
Tuesday night saw Ashton United pass up on the chance to set up an all-Ashton Manchester Premier Cup Final, with Tameside neighbours Droylsden picking up a shock semi-final victory at Hurst Cross.
Following their loss at home to Real Madrid last week, knocking them out of the Champions League, Manchester City faced arguably a tougher test against Arsenal in the Carabao Cup Final on Sunday.